Yes. Many refurbished Apple products have spent their short life being used by their previous owner, or being used by multiple people as a display model in a store. That is why it’s so important for refurbished phones, tablets and computers alike, to go through an intense cleaning process.
Products are thoroughly cleaned to ensure they are as shiny and dust-free as new. Screens are polished, dust is removed from keyboards, and all ports are checked for dirt. Also, the internal parts of the hardware are cleaned so that you can be sure the refurbished device is completely spotless and sanitized.